The Impact Of Surgical Glue Use As A Biliostatic and Hemostatic Agent During Liver Resection In Pediatric Patients

Document Type : Original Article

Authors

Department of Pediatric Surgery, Faculty of Medicine, Cairo University, Egypt

10.21608/ejsur.2025.351929.1355

Abstract

Background: Paediatric liver resection presents unique challenges, particularly in achieving effective haemostasis and
biliostasis. surgical glue is a synthetic surgical adhesive material composed primarily of modified n-butyl-2-cyanoacrylate,
has shown a promise in various surgical applications. This study aimed to evaluate the impact of the surgical glue
application on alleviation of postoperative complications in paediatric liver resections.
Patients and Methods: This retrospective study was conducted on 22 paediatric patients underwent liver resection, those
receiving intraoperative surgical glue on the transacted liver surface. the current research was planned to investigate the
mitigating action of the surgical glue on the hepatic resection related biliary leakage and bleeding.
Results: The mean age was 3.1 years (±3.15). Hepatoblastoma was the most common pathology (50%). Right hepatectomy was performed in 59.09% of cases. Following the application of the surgical glue, postoperative biliary leakage showed no effect when compared with the results in literature, occurring in 18.18% of patients, with varying degrees of severity. however, the incidence of postoperative bleeding was markedly improved, observed in just 5.26% of patients. The mean hospital stay was 11.6 days (±4.94), ranging from 3 to 22 days.
Conclusion: This study highlights the use of a haemostatic and a biliostatic agent like surgical glue that may potentially
impact the outcome after liver resection in paediatric patients regarding bleeding.

Keywords

The Egyptian Journal of Surgery
Volume 44, Issue 3
July 2025
Pages 1002-1007

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