Impact of Nerve-Sparing Radical Hysterectomy on Pelvic Dysfunctions and Overall Quality of Life in Cervical Cancer: A Comparative Clinical Study

Document Type : Original Article

Authors

Department of Surgical Oncology, National Cancer Institute, Cairo University, Cairo, Egypt

Abstract

Background and Aims: The study aims to compare pelvic dysfunctions and quality of life in cervical cancer patients
following nerve-sparing radical hysterectomy (NSRH) and conventional radical hysterectomy (CRH), and to assess the
oncologic safety of NSRH through comparing survival outcomes of both techniques.
Patients and Methods: All patients with stages I and II cervical cancer at the National Cancer Institute, Cairo University
who underwent NSRH or CRH from 2016 to 2018 were included in the study and were assessed for pelvic dysfunctions
and survival outcomes.
Results: Fifty-two patients were enrolled in the study. A study group (NSRH group) of 25 patients and a control group
(CRH group) of 27 patients. All patients signed an informed consent after a detailed account of the procedure, its expected outcome, and complications had been explained to them. The incidence of urine retention, urinary incontinence, severe constipation, and sexual dysfunction was higher among the CRH patients. There was a slight difference in disease-free survival and overall survival in both groups.
Conclusion: The severity of pelvic dysfunctions was less after NSRH. NSRH is an oncologically safe technique as well.

Keywords

The Egyptian Journal of Surgery
Volume 44, Issue 2
April 2025
Pages 638-645

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