THE FATE OF INTRAPERITONEAL IMPLANTED GALLSTONES IN DOGS

I. Nafeh, Ayman; Abbas, Mohamed; El Damarawy, Mervat; Abou El Fadi, Laila; Hammam, Oulfat; Hussein, Ahmed; Abdel Halim, AIaa; AL Kholy, Badawy

doi:10.21608/ejsur.2001.376353

THE FATE OF INTRAPERITONEAL IMPLANTED GALLSTONES IN DOGS

Document Type : Original Article

Authors

¹ Surgical Departments, Theodor Bilharz Institute

² Intensive care Departments, Theodor Bilharz Institute

³ Bacteriology Departments, Theodor Bilharz Institute

⁴ Pathology departments Theodor Bilharz Institute

⁵ Surgical Departments. Alexandria University

⁶ Surgical departments, Bani sweif Branch6 Cairo Universities and Chemical Clinical

⁷ Pathology Department, Cairo University, Egypt.

10.21608/ejsur.2001.376353

Abstract

Introduction: Little is Known about the natural history of gallstones left behind in the peritoneal cavity during
laparoscopic cholecystectomy .
Aims: This experimental study was conducted to assess the consequence of implanted intra- abdominal gallstones in
dogs.
Materials and methods: Eighty four male mongrel dogs were divided into: G1 (n =12), G2 (n=36) and G3 (n =36) Where
sterile glass beads with sterile saline , collected bile with different types of gallstones (subgroups) and enriched bile
(E.Coli & Staph. aureus) with gallstones were implanted in an omental pouch respectively.
The gallstones and bile were collected from 50 gallbladders resected from patients with chronic calcular cholecystitis.
Half the number of dogs from each group was re- explored after one week and the rest after six weeks, so as to retrieve
the implants with their surrounding tissues for histopathological examination.
Acute inflammatory reaction with different degrees of intensities of polymorphonuclear leucocytes and macrophages
were noted in G1 and G2 after one week which completely disappeared six weeks postoperatively. In G3, severe acute
inflammatory reaction and abscess formation were observed one week postoperatively, but markedly resolved in animals
explored after six weeks without antibiotic coverage.
Conclusions: This study revealed that intraperitonal lost gallstones cause no serious tissue reaction in dogs. We suggest
that lost gallstones during laparoscopic cholecystectomy, unless easy to retrieve, should not prolong the operation time or justify conversion to laparotomy.