Background: After splenectomy, patients have an increased risk of overwhelming infection. The value of human spleen autotransplantation after splenectomy because of trauma has long been questioned. The aim of this work is to study (experimental and applied) the effect of partial splenic autotransplantation (PSA) on haematological changes and some immunological splenic functions. Methods: The present study was conducted on 45 patients and 60 rabbits divided into groups underwent either total splenectomy only, total splenectomy with intraperitoneal partial splenic autotransplantation (IPPSA) or total splenectomy with extraperitoneal partial splenic autotransplantation (EPPSA). Another group of 15 rabbits underwent total splenectomy with intramuscular partial splenic autotransplantation (IMPSA). Haematological changes and serum immunoglobulins (IgM, IgA, IgG) were studied on days 1, 30 and 90 postoperatively. Results: Both experimental and applied groups underwent PSA showed preservation of the splenic immunological functions and insignificant haematological changes irrespective of the site of autotransplantation. The vascularity of the autotransplanted splenic slices depends on the optimum size of the slice, (5 mm in thickness). Conclusion: With extensive splenic trauma, total splenectomy with PSA can be performed safely with insignificant haematological changes and preservation of splenic immunological functions.
I. Moussa, G., H. El Khadrawy, O., Issa, A., A. Eltablawy, M., A. Baza, O., Abdel Aziem, S., M. El Shiekh, M., & E. Asker, S. (2002). SPLENIC AUTOTRANSPLANTATION “EXPERIMENTAL AND APPLIED STUDY”. The Egyptian Journal of Surgery, 21(4), 1043-1050. doi: 10.21608/ejsur.2002.374949
MLA
Gamal I. Moussa; Osama H. El Khadrawy; Ahmed Issa; Mostafa A. Eltablawy; Osama A. Baza; S. Abdel Aziem; Mahmoud M. El Shiekh; Said E. Asker. "SPLENIC AUTOTRANSPLANTATION “EXPERIMENTAL AND APPLIED STUDY”", The Egyptian Journal of Surgery, 21, 4, 2002, 1043-1050. doi: 10.21608/ejsur.2002.374949
HARVARD
I. Moussa, G., H. El Khadrawy, O., Issa, A., A. Eltablawy, M., A. Baza, O., Abdel Aziem, S., M. El Shiekh, M., E. Asker, S. (2002). 'SPLENIC AUTOTRANSPLANTATION “EXPERIMENTAL AND APPLIED STUDY”', The Egyptian Journal of Surgery, 21(4), pp. 1043-1050. doi: 10.21608/ejsur.2002.374949
VANCOUVER
I. Moussa, G., H. El Khadrawy, O., Issa, A., A. Eltablawy, M., A. Baza, O., Abdel Aziem, S., M. El Shiekh, M., E. Asker, S. SPLENIC AUTOTRANSPLANTATION “EXPERIMENTAL AND APPLIED STUDY”. The Egyptian Journal of Surgery, 2002; 21(4): 1043-1050. doi: 10.21608/ejsur.2002.374949
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