FEASIBILITY AND OUTCOME OF SURGICAL RESECTION OF HEPATOCELLULAR CARCINOMA

Document Type : Original Article

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Department of General Surgery, Faculty of Medicine, Alexandria University

Abstract

Introduction: Hepatocellular carcinoma is the fifth most common tumor world-wide. Two- thirds of 
hepatocellular carcinoma tumors are first diagnosed at advanced stages with consequent dismal prognosis. 
There are different treatment algorithms. 
Aim: of this study was to assess the feasibility and outcome of resection of hepatocellular carcinoma tumors. 
Methods: This study included 215 consecutive patients with hepatocellular carcinoma. Triphasic CT, Child`s 
classification and intraoperative ultrasonography were used to assess resectability. Resection was done for 
solitary tumors in Child A or B patients preserving at least 50% of total liver volume. 
Results: The median age was 58 years. There were 146 males (67.9 %) and 69 females (32.1%). Resection was 
feasible for 36 (16.7%) patients. Postoperative complications occurred in 8 (22.2%) patients with 1-, 2- and 3-
year survival rates 69.4%, 47.2% and 41.6% respectively. 
Conclusions: Feasibility of hepatic resection was limited for 16.7% patients. By meticulous assessment, 
resection could be the best treatment for many tumors larger than 5 cm in diameter. Non-anatomical 
resection was valuable to allow resection of selected tumors with preservation of sufficient liver tissue. 
There is controversy in feasibility of surgery among algorithms.

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