Aim: To evaluate patients with gall bladder carcinoma to define the demographics, modes of presentations, clinical staging, pathological characters and survival. Methods: A retrospective study on 80 patients with gall bladder carcinoma at Gastroenterology Surgical Center, Mansoura University between 1990 to 2012. There were 45 males & 35 females with an average age of 53 years. Patients were classified according to the mode of presentation into four groups and the treatment modalities were according to presentation, state of the tumor & associated liver condition. All patients were followed up by ultrasound (or CT) every 6 months postoperatively. Survival was monitored with respect to the histological type of the tumor & stage of the disease. Results: Gall bladder carcinoma represented 1.3% of a total of 5980 cases of abdominal malignancies in our center. HCV infection was present in 15% and associated gall stones in 45% of patients. We had 40 (50%) patients with gall bladder mass or obstructed gall bladder, 23 (28.75%) with symptomatic gall stones, 15 (18.75%) with obstructive Jaundice and 2 (2.5%) with gastrointestinal bleeding. Extended cholecystectomy done in 32 (4o %) patients but nothing done for 26 (32.5%) patients due to advanced tumor . Right hepatectomy was done for 12 (15%) patients due to infiltration of right liver lobe & right hepatic duct. Laparoscopic cholecystectomy was done for 8 (10%) patients as tumour was discovered accidentally. Extended cholecystectomy plus right hemicolectomy for one patient & for the last patient extended cholecystectomy was done with pancreaticodudenectomy. Survival was from 8-43 months according to line of treatment, but 5 year- survival was zero percent. Conclusion: Gall bladder carcinoma is not uncommon with poor prognosis. Prevention is important & routine postoperative histopathology is mandatory.
Abel Wahab, M., El-Hemaly, M., El-Nakeeb, A., Hamdy, E., Askar, W., El Hanafy, E., Atef, E., & Soultan, A. (2012). GALL BLADDER CARCINOMA: OUR INSTITUTIONAL EXPERIENCE. The Egyptian Journal of Surgery, 31(3), 103-109. doi: 10.21608/ejsur.2012.367256
MLA
Mohamad Abel Wahab; Mohamad El-Hemaly; Aymen El-Nakeeb; Emad Hamdy; Waleed Askar; Ehab El Hanafy; Ehab Atef; Ahmad Soultan. "GALL BLADDER CARCINOMA: OUR INSTITUTIONAL EXPERIENCE", The Egyptian Journal of Surgery, 31, 3, 2012, 103-109. doi: 10.21608/ejsur.2012.367256
HARVARD
Abel Wahab, M., El-Hemaly, M., El-Nakeeb, A., Hamdy, E., Askar, W., El Hanafy, E., Atef, E., Soultan, A. (2012). 'GALL BLADDER CARCINOMA: OUR INSTITUTIONAL EXPERIENCE', The Egyptian Journal of Surgery, 31(3), pp. 103-109. doi: 10.21608/ejsur.2012.367256
VANCOUVER
Abel Wahab, M., El-Hemaly, M., El-Nakeeb, A., Hamdy, E., Askar, W., El Hanafy, E., Atef, E., Soultan, A. GALL BLADDER CARCINOMA: OUR INSTITUTIONAL EXPERIENCE. The Egyptian Journal of Surgery, 2012; 31(3): 103-109. doi: 10.21608/ejsur.2012.367256