FEASIBILITY OF LEFT LOBE GRAFT IN ADULT LIVING DONOR LIVER TRANSPLANTATION

Document Type : Original Article

Authors

1 Armed Forces College of Medicine

2 Department of Surgery, Faculty of Medicine, Alazhar University

3 Department of Pediatric Surgery & Transplantaiton, Kumamoto University, Kumamoto, Japan

4 Foundation for Kobe International Medical Alliance, Kobe, Japan

Abstract

The objective: of this study is to assess the feasibility of LLG as an option in the Adult Living Donor Liver 
Transplantation. The study aims to consider the anatomical advantages of the Left Lobe Graft, the safer 
Donor's hepatectmy and to innovate criteria for Left Lobe Graft selection. Data on 34 consecutive LL LDLTs, 
including two retransplants, were retrospectively compared with those of 34 RL LDLTs, in terms of survival, 
complications and donor morbidity. The mean GRWR of LL grafts was 0.71% whereas that of RL grafts was 
0.88%. The 1-year patient survival rates of LL LDLT were 85.3%,, which were comparable to those of RL LDLT 
(85.3%). The incidence of small-for-size syndrome was higher in LL LDLT (11.8%) than in RL LDLT (5.9%). 
The overall donor morbidity rates were comparable between LL (20.5%) and RL (14.7%), whereas 
postoperative liver function tests and hospital stay were significantly better in LL donors. 
Conclusion: Adult LL LDLT has comparable outcomes to that of RL LDLT. To minimize the risk to the donor, 
LL-LDLT could be an ideal option in adult-to-adult LDLT.