Evaluation of the outcome of laparoscopic one anastomosis gastric bypass among obese patients with type 2 diabetes mellitus; a prospective study

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Abstract

Background
Laparoscopic one-anastomosis gastric bypass (OAGB) was introduced as a simple (one anastomosis) operation combining both restrictive and malabsorptive functions, thus suitable for obese patients with metabolic derangements like type 2 diabetes mellitus (T2DM). The aim of this study was to evaluate the outcome of OAGB among obese patients with T2DM.
Patients and methods
A sample of 40 individuals with a BMI greater than 35 kg/m and T2DM was prospectively recruited from the obesity clinic, Suez Canal University teaching hospital and Suez Canal Authority hospital, city of Ismailia, Egypt. The patients underwent laparoscopic OAGB operation and were offered a follow-up for a period of 12 months.
Results
The mean;Deg;BM;Deg;I of the patients demonstrated a statistically significant decline from 49.2 kg/m preoperatively to 34.2 kg/m at the end of the follow-up. Regarding diabetes status, the mean fasting blood sugar decreased significantly from 226 to 104 mg/dl. Moreover, the mean glycosylated hemoglobin decreased from 8.4 to 6.3%. Overall, 42.5% of the patients showed complete diabetic remission at the end of the follow-up, whereas 35% showed partial remission. The rest of the patients (22.5%) did not fulfill the criterion, yet showed improvement in their fasting blood sugar and glycosylated hemoglobin levels from their preoperative values.
Conclusion
Laparoscopic OAGB had proved to be an effective surgical treatment for both obesity and T2DM.

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